فهرست نشریات علمی دسترسی آزاد ایران

Background and Objective: Acute appendicitis is traditionally treated with operative approaches. Thelatest progress in diagnostic techniques has coincided with the introduction of novel non-invasive treatmentoptions. Original studies on this subject indicate that non-operative management of acute appendicitis in thechildren population is feasible. This review explores current literature on the efficacy, safety, and long-termoutcomes of non-operative treatments and gives an overview of this management method.Materials & Methods: In the pursuit of conducting this narrative review, a systematic search wasperformed utilizing the Scopus, Embase, ISI, and Google Scholar databases. The inclusion criteria comprisedoriginal articles, review papers, and meta-analyses that focus on the non-surgical treatment of acuteappendicitis in the pediatric population. This investigation adopted a descriptive-analytical approach. Allpertinent literature was meticulously evaluated, and data were carefully extracted; the findings and insightsobtained from these sources were subsequently incorporated into various sections of this review.Results: Non-operative management has been reported to have a lesser length of hospital stay and abetter patient satisfaction rate in comparison to operative management. Key factors in selecting theappropriate patients for non-operative management include younger age, lesser symptoms and feverdurations, mild clinical presentations, lower white blood cell and CRP levels on laboratory studies, and lowerappendix diameter on imaging. Further Randomized Controlled Trials with longer follow-up durations andsimilar antibiotic administration are required to address the heterogeneity of previous research.Conclusion: Existing evidence from previous studies advocates for the non-surgical management ofuncomplicated acute appendicitis in children. However, it is imperative to establish comprehensiveguidelines for patient selection. Such guidelines are essential to mitigate the risk of misdiagnosis and toprevent the occurrence of serious complications stemming from inadequate management.