فهرست نشریات علمی دسترسی آزاد ایران

Background and Objective: Diabetes is recognized as a major factor contributing to seriouscomplications that may lead to the need for limb amputation. This study was designed to investigate theincidence and identify risk factors associated with re-amputation in diabetic patients undergoingamputation.Materials & Methods: This research is a case-control study conducted on diabetic patients undergoingamputation at Shahid Beheshti Medical Center in Qom. Data were collected by reviewing patients' medicalrecords. The collected information included age, gender, duration of diabetes, medical history, postoperativeinfection, vascular problems, and smoking history, which were recorded and compared between the twogroups: those with and without re-amputation. Data were analyzed using SPSS version 26 with statisticaltests including t-tests and chi-square tests. A significance level of 0.05 was considered for all tests.Results: Among the 137 patients who underwent amputation, 36 patients were re-amputated withinthe following 18 months. Statistical analysis indicated that only the site of amputation showed a statisticallysignificant difference between the two groups with and without re-amputation (P < 0.05). Other risk factorssuch as age, length of hospital stay, gender, smoking status, urgency of surgery, cardiovascular diseases, endstagerenal disease (ESRD), immunosuppressive therapy, and the incidence of postoperative infection did notshow statistically significant differences between the two groups (P > 0.05).Conclusion: This study demonstrates that above-knee amputation is primarily associated with the needfor re-amputation, while other factors such as age, length of stay, gender, and smoking do not have asignificant impact. Future research is recommended to focus on increasing sample size and long-term followupof patients to improve treatment quality.