فهرست نشریات علمی دسترسی آزاد ایران

Background and Objective: Endometrial polyps are common disorders within the female reproductivesystem that can significantly impact women's reproductive health and overall quality of life. The prevalencerates for these polyps vary from 7.8% to 34.9%, with reported figures in Iran ranging between 15% and 20%.Given their potential for malignancy as well as their association with abnormal bleeding and infertility, thisstudy aims to investigate the frequency of malignant lesions among women diagnosed with endometrialpolyps over a decade-long period in Tehran.Materials & Methods: This cross-sectional study included women who underwent hysterectomy at aclinic in Tehran from 2013 to 2023 due to menstrual issues, infertility concerns, or episodes of abnormalbleeding. Data were collected on the prevalence of endometrial polyps along with pathological findings frombiopsy samples taken from these lesions. Additionally, patient age and tumor size were recorded forsubsequent analysis. The data were analyzed using SPSS software employing ANOVA tests as well as Pearsoncorrelation coefficient analysis and regression analysis; a significance level (P) less than 0.005 was consideredsignificant.Results: Among a total of 1,488 patients who underwent hysteroscopy during the specified period,endometrial polyps were identified in 68 individuals. The mean age of these patients was determined to be41.3 years; notably, approximately 40% fell within the age bracket of 40-50 years old. Pathologicalexamination revealed that malignancies constituted only about 1.6%, while benign lesions accounted forapproximately 95.5%; pre-malignant lesions comprised around 2.9%. A statistically significant positivecorrelation was identified between patient age and tumor size (P < 0.005; r = 0.6), along with an increasedlikelihood of malignancy associated with larger tumor sizes (P < 0.001).Conclusion: This study underscores a high prevalence rate of benign endometrial polyps particularlyamong older women while also highlighting the importance of identifying risk factors related to malignancyand closely monitoring larger polyps for potential cancerous changes.