فهرست نشریات علمی دسترسی آزاد ایران

Background and Objective: There is a known relationship between cardiovascular diseases and lowlevels of vitamin D. Previous studies on the effects of vitamin D supplementation on triglyceridelevels, a key indicator of cardiovascular health, have shown conflicting results. This study aims to summarizethe findings of these studies. The purpose of this systematic review and meta-analysis is to investigate theeffects of vitamin D supplementation on triglyceride levels in obese children who are candidates for surgery.Materials & Methods: This study was conducted following the PRISMA statement guidelines.Databases searched included Scopus, Mag Iran, SID, Web of Science, PubMed, and Embase for randomizedclinical trial studies published up to the end of 2021. Both Farsi and English studies were included. Searchkeywords were: cholesterol, triacylglycerol, triglyceride, heart risk, metabolic syndrome, child, adolescent,student, school, school age, childhood, vitamin D, 25-hydroxy vitamin D.Results: The meta-analysis revealed no significant difference in triglyceride levels at the end of the studycompared to the beginning (MD = 5.23-2.92 mg/dl, 95% CI: 59%, I2 = 0.21-2.92, P). However, high levels ofvitamin D supplementation (more than 200,000 units during the treatment period) led to a significantdecrease in triglycerides (MD = -5.08 mg/dl, 95% CI: -83.00 to -4.15, I2 = 64%, P = 0.31).Conclusion: High levels of vitamin D supplementation significantly decrease triglyceride levels in obesechildren who are candidates for surgery compared to lower levels of supplementation.