Limbic Encephalitis Driven by a Pleural Mesothelioma: A Paraneoplastic Complication

نویسندگان

1 Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, UK

2 University of Exeter Medical School, Exeter, Devon, UK

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چکیده

Paraneoplastic neurological syndromes have only been described with pleural mesothelioma in five cases. We have described a 72-year-old man who developed anterograde amnesia 27 months after diagnosis of epithelioid pleural mesothelioma. Investigations revealed a limbic encephalitis with no alternative causes identified. Limbic encephalitis is a classical paraneoplastic syndrome and presentation within five years of a cancer with no other causes identified is sufficient to diagnose a paraneoplastic etiology. This is the first case of isolated paraneoplastic limbic encephalitis driven by a pleural mesothelioma.

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