فهرست نشریات علمی دسترسی آزاد ایران

Background: Growing antibiotic resistance demands the constant reassessment of antimicrobial efficacy, particularly in countries with wide antibiotic abuse. Knowledge of resistance trends is particularly important when prescribing antibiotics empirically, as is usually the case for urinary tract infections (UTIs) especially in children with terminal renal failure on continuous ambulatory peritoneal dialysis (CAPD) treatment. The aim of this study was to analyze the resistance of bacterial isolates to commonly used antibiotics in such patients. Results: The most prevalent urinary pathogen was Escherichia coli from 27 cases (75%). In general, the lowest resistance rate of microorganisms was against amikacin (3.7%) and the highest resistance rate was against amoxicillin (70.4%). Conclusion: A comparison of these data with those of other countries showed that there was considerable geographic variation in bacterial patterns of sensitivity and resistance properties. Therefore, the selection of antibiotics for empiric therapy especially in children with terminal renal failure on continuous ambulatory peritoneal dialysis (CAPD) treatment should be based on the knowledge of the local conditions.