Timing of Prophylactic Antibiotic Administration in Term Cesarean Section: A Randomized Clinical Trial
نویسندگان
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doi
چکیده
Background: Antibiotic prophylaxis would benefit all cesarean section patients and may decrease morbidity and length of hospital stay. The present study was conducted to determine whether the administration of cefazolin prior to skin incision was superior to administration at the time of umbilical cord clamping for prevention of post-cesarean maternalneonatal infections morbidity. Results: Two groups were demographically identical. Rate of IV line need (RR=1.87, 95%CI:0.21-17.02), neonatal sepsis (RR=1.39, 95%CI:0.14-13.64) and NICU admission (RR=0.19, 95%CI: 0.21-17.02) were not significantly differed between groups. Conclusion: We suggest the standard cefazolin prophylaxis (after cord clamping) for elective cesarean section and cefazolin before incision for non elective cesarean section. Therefore, administration of prophylactic cefazolin prior to incision will not increase the rate of neonatal sepsis.