فهرست نشریات علمی دسترسی آزاد ایران

Background: Chronic sinusitis is one of the most common medical problems affecting 30 million people in USA annually. In the present study, we compared the efficacy and safety of clarithromycin XL and co-amoxiclav on clinical and CT scan findings of patients suffering from chronic sinusitis. Results: Clinical success rates were similar at the end of therapy period, however, subjects receiving clarithromycin XL showed better CT scan findings when compared with co-amoxiclav-treated subjects (53% versus 29%). Gastrointestinal discomfort was the most frequent treatmentrelated adverse effects in both groups (NS). Conclusion: Results revealed that clarithromycin XL and co-amoxiclav have similar efficacy when considered for treatment of chronic sinusitis.