فهرست نشریات علمی دسترسی آزاد ایران

Background: In spite of many advantages of modern medicine in comparison with traditional treatments, chemical therapeutic agents have side effects. Pistachio skin extract has antibacterial effects, but side effect has not been reported Objectives: The aim of this study was to compare the effects of pistachio skin extract with that of antibiotics such as amoxicillin, tetracycline, cefixime and ciprofloxacin, on enteric bacteria collected from patients with gastroenteritis. Results: Shigella with 19% sensitivity and 1% resistance had the highest sensitivity and the lowest resistance to each of the antibiotics, including tetracycline, amoxicillin and ciprofloxacin; this difference was statistically significant (P < 0.05). The results showed that Escherichia coli with 13.6 mL sensitivity and 6.4 mL resistancy was the bacteria, for which antibiotics were least effective (amoxicillin: P = 0.000, tetracycline: P = 0.049, cefixime: P = 0.000); this finding was statistically significant (P < 0.05). Conclusions: Regarding the natural therapeutic effects of pistachio skin extract and obligations of the routine antibiotics such as resistancy, using pistachio extract as a co-therapeutical agent with ordinary antibiotics can enhance the success rate of the treatment.