Co-occurrence of Extended-Spectrum Beta-Lactamases in Isolated Enterobacter spp. From Patients Specimens
نویسندگان
1 دانشگاه تهران
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doi
10.5812/archcid.26837چکیده
Background: Clinical significance of Extended-Spectrum Beta-Lactamases (ESBLs) production in Enterobacter spp. has not well been established. Objectives: This study was conducted to investigate the prevalence of ESBLs produced by Enterobacter spp. in clinical isolates. Results: Out of 118 Enterobacter spp. isolates, 31.36% were Enterobacter aerogenes ( E. aerogenes ), 20.34% Enterobacter agglomerans ( E. agglomerans ), 12.71% Enterobacter cloacae (E. cloacae), and 33.90% were other Enterobacter spp. All 118 (100%) Enterobacter isolates produced ESBLs. In the detection of ESBLs, CDT and PCR results were similar to each other and all 118 Enterobacter spp. were ESBLs producers (κ = 1). Conclusions: According to the results, most of the Enterobacter spp. produced ESBLs and were Cefotaxime-M (CTX-M) enzyme carriers. Guidelines and appropriate use of antibiotics are necessary to avoid the production of ESBLs.