فهرست نشریات علمی دسترسی آزاد ایران

Antimicrobial peptides are cationic molecules, which participate in multiple aspects of the immune responseincluding the control of inflammatory diseases, characteristic that make these molecules attractive astherapeutic tools. These peptides are produced in bacteria, insects, plants and vertebrates, and are classifiedtogether due to their capacity to directly inhibit the growth of microorganisms, and to regulate the immuneresponse by inducing the secretion of chemokines and cytokines. Various families of antimicrobial peptideshave been identified including the cathelicidins and defensins, the most investigated human antimicrobialpeptides. This review will cover the main biological functions of antimicrobial and cell-penetrating peptidesin inflammation, and describe the importance and utility of antimicrobial peptides as therapeutics forinflammatory diseases.