فهرست نشریات علمی دسترسی آزاد ایران

Chronic cervicitis is a clinical syndrome characterized by persistent inflammation of the cervical epithelium. Womenwith chronic cervicitis often experience symptoms such as vaginal discharge, dyspareunia, post-coital bleeding, andfatigue. The treatment of chronic cervicitis is controversial, particularly in cases where no specific pathogenic agent beidentified. Natural wound dressings with human amniotic membranes have been successfully used in tissue healingprocedures. Thus, this approach may be a potential therapeutic option for patients suffering from chronic cervicitis. Thiscase series reports on five women diagnosed with chronic cervicitis. These patients had negative Pap smears, humanpapillomavirus (HPV) typing tests, and colposcopic biopsies, indicating no infections or malignancies. Despite receivingoral antibiotics, their symptoms did not improve, leading to the decision to treat them with amniotic membrane. Thecervix was assessed using a speculum, and amniotic membranes manufactured by Sinacell Company were insertedinto the affected cervical areas. The patients were instructed to avoid sexual intercourse for one week and continueusing oral antibiotics. At the follow-up, all patients significantly improved without any adverse events. Additionally,colposcopic examinations revealed that most patients showed improvement in cervical inflammation and bleeding. Theamniotic membrane can assist women with chronic cervicitis by alleviating symptoms and enhancing the healing ofcervical ulcers without complications.