The Resistance Training Effects on Skeletal Muscle Stem Cells in Older Adult: A Systematic Review and Meta-Analysis
نویسندگان
1 Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
2 Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
3 Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
4 Exercise Physiology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
doi
10.22074/cellj.2023.1986679.1206چکیده
The objective of this systematic review and meta-analysis is to examine the effects of resistance exercise trainingon muscle stem cells in older adults. A database search was performed (PubMed, Scopus, Web of Science andGoogle Scholar) to identify controlled clinical trials in English language. The mean difference (MD) with 95% confidenceintervals (CIs) and overall effect size were calculated for all comparisons. The PEDro scale was used to assess themethodological quality. Nineteen studies were included in the review. The meta-analysis found a significant effect ofresistance training (RT) on muscle stem cells in the elderly (difference in means=-0.008, Z=-3.415, P=0.001). Also,muscle stem cells changes were similar in men and women (difference in means=-0.004, Z=-1.558, P=0.119) andsignificant changes occur in type II muscle fibers (difference in means=-0.017, Z=-7.048, P=0.000). Resistance-typeexercise training significantly increased muscle stem cells content in intervention group that this result is similar in menand womenthis increase occurred more in type II muscle fibers.
