فهرست نشریات علمی دسترسی آزاد ایران

This study investigates the potential of Coconut Seed Coat Ash (CSCA) as a sustainable and environmentally friendly green catalyst. CSCA was prepared by controlled combustion of coconut seed coat and husk at 500 °C in a muffle furnace, ensuring consistent results and complete combustion. The study highlights the advantages of using CSCA, including its low cost, abundance, and renewable nature, making it a promising catalyst for facilitating chemical reactions without being consumed. Utilizing CSCA at a concentration of 30 mmol/L, a series of 2-amino-4H-benzopyran derivative was synthesized through a reaction between aromatic aldehydes, dimedone, and malononitrile. This green approach proved cost-effective, practical, and efficient, offering high yields and simple work-up procedures. The synthesized compounds were characterized using IR spectroscopy, mass spectrometry (MS), proton nuclear magnetic resonance (¹H-NMR), and elemental analysis. Furthermore, the antimicrobial activity of the compounds was evaluated against bacterial strains ( Staphylococcus aureus MCC 2010, Bacillus subtilis MCC 2010, Escherichia coli MCC 2412, and Pseudomonas aeruginosa MCC 2080) and yeast strains ( Candida albicans MCC 1439 and Saccharomyces cerevisiae ). The synthesized compounds exhibited notable spectral peaks in FTIR, ¹H-NMR, and UV analyses and demonstrated superior antibacterial and antifungal activities in vitro compared to standard antibiotics streptomycin and fluconazol.