Optimization of Green Synthesis of Nickel Nanoparticles by Halomonas Elongata as Antifungal Agent
نویسندگان
1 دانشگاه اصفهان
2 دانشگاه تهران
3 دانشگاه تهران
4 دانشگاه تهران
5
6
7 دانشگاه فردوسی مشهد
8
9 دانشگاه رازی
doi
10.48309/AJGC.2024.484242.1574چکیده
The current study aimed to investigate the optimum conditions for the green synthesis of nickel nanoparticles (NPs) with the highest antimicrobial activity instead of the Candida albicans . To this end, nine experiments were designed using the Taguchi method, and nickel NPs were synthesized biologically using the bacterium Halomonas elongata . According to the findings, the most suitable level for nickel nitrate, incubation temperature, and incubation duration was the third level (0.7 M), the second level (32 °C) and the first level (48 h), respectively. It was calculated that the NPs under synthesis in optimum conditions inhibited more than 72% of fungal growth. Moreover, the current study examined the features of nickel NPs under synthesis by various analyses that confirmed the formation of nickel NPs with favorable structural and morphological properties . Therefore, these nanoparticles can be used in medicine and dentistry as an effective antifungal compound.
