An Effectual Eco-Friendly Protocol for the Construction of 4,6-Diarylpyrimidin-2(1H)-Ones

نویسندگان

1 دانشگاه علامه طباطبایی

2

doi
10.48309/ajgc.2024.457824.1508
چکیده

An effectual eco-friendly protocol for the construction of 4,6-diarylpyrimidin-2(1 H )-ones has been described through a solvent-free one-pot multi-component reaction. The condensation of urea, aryl aldehydes, and acetophenones in the Me 3 SiCl presence produced 4,6-diarylpyrimidin-2(1 H )-ones in high yields and relatively short times. In the reported protocols, a catalyst has been used beside Me 3 SiCl. However, in our protocol, there was no need to utilize a catalyst.