فهرست نشریات علمی دسترسی آزاد ایران

Background: Lichen striatus (LS) is a rare, self-limiting inflammatory dermatosis characterized by distinct clinical and histopathological features. This study aimed to evaluate the demographic, clinical, and histopathological characteristics of LS. Methods: This retrospective case series included all patients diagnosed with LS at Razi Hospital, Tehran, Iran, from 2019 to 2023, based on biopsy and histopathological examination. Data were collected from archived patient records and included demographic details, lesion characteristics, disease duration, seasonal distribution, and histopathological findings. Statistical analysis was performed using IBM SPSS Statistics. Quantitative variables were expressed as means ± standard deviations (SD), and categorical variables were presented as frequencies and percentages. Results: Among 50 patients, 18 (36%) were male and 32 (64%) were female. The age range was 1 to 74 years, with a mean of 24.32 ± 16.62 years. The highest prevalence was observed in the 0–10-year age group. The lower extremities were the most commonly affected sites (26% in females and 14% in males). Most lesions appeared during autumn and winter. The average disease duration was 7.6 months. A positive family history was noted in only one patient, while four patients had a history of similar lesions. Lymphocytic infiltration (94%) was the most common histopathological finding, followed by lichenoid reaction (68%), whereas Civatte bodies were the least frequently observed feature. Conclusion: This study highlights the predominance of LS in females, young adults, and the lower limbs. Lymphocytic infiltration remains the hallmark histopathological feature. The findings support the self-limiting nature of LS and its minimal hereditary influence.