Association between allergic contact dermatitis and frontal fibrosing alopecia: a narrative review
نویسندگان
1 Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Department of Dermatology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
3 Department of Dermatology, Mazandaran University of Medical Sciences, Sari, Iran.
4 Mazandaran University of Medical Sciences, Sari, Iran
5 Department of Dermatology, Yale School of Medicine, Yale University, New Haven, Connecticut, USA
doi
10.22034/ijd.2024.493229.1942چکیده
Frontal fibrosing alopecia (FFA), a type of primary cicatricial alopecia, has an unknown exact pathogenesis, which may be influenced by environmental factors. Allergic contact dermatitis (ACD) is a frequently observed comorbidity in patients with FFA. In this article, we analyze the potential association between ACD and FFA by reviewing the published literature from PubMed and Google Scholar. We examined relevant articles related to ACD and contact allergens in FFA patients published since 2012. The use of cosmetics and facial products among FFA patients is significantly higher than in the healthy population. The presence of ACD in conjunction with FFA can be indicated by one or more positive patch test reactions to common contact allergens found in everyday products, particularly cosmetics and facial products. Contact allergens identified in patients with FFA include nickel sulfate, benzyl salicylate, gallates, propolis, limonene hydroperoxides, cobalt(II) chloride hexahydrate, alkylphenolic compounds, and linalool. Overall, the literature suggests that ACD is prevalent among patients with FFA and may play a role in its pathogenesis.
