فهرست نشریات علمی دسترسی آزاد ایران

Mucoepidermoid carcinoma is a malignant epithelial neoplasm and the most common malignant tumor of the salivary glands. Although it primarily occurs in the salivary glands, it can rarely be found in other locations, such as the sinonasal tract, nasopharynx, lungs, and intraosseous mandible. This tumor is more frequently diagnosed in middle-aged adults. Overall survival rates are highly dependent on the tumor’s histologic grade, with a significant decrease in survival associated with higher grades. The five-year survival rate is approximately 98% for low- and intermediate- grade tumors, while it drops to about 67% for high-grade tumors. In this report, we present an extremely rare case of primary mucoepidermoid carcinoma in an 88-year-old man who exhibited a nodular lesion on the left temporal side of the scalp. Histopathological examination revealed glandular and squamous differentiation, and an immunohistochemical studies, including CK7, P63, and EMA, confirmed the diagnosis. This case is presented due to its rarity and emphasizes the importance of adequate sampling for accurate diagnosis.