فهرست نشریات علمی دسترسی آزاد ایران

Introduction: This study aimed to compare the treatment planning volumes and the integral doses (ID) during radiotherapy for prostate cancer using three-dimensional conformal radiotherapy (3D-CRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated arc therapy (VMAT) techniques.Material and Methods: The study included 10 patients treated in our clinic, diagnosed with intermediate risk prostate cancer at the T2bN0M0 stage, Gleason score ≤ 7 and prostate-specific antigen (PSA) levels between 10-20 ng/mL. For each patient, 6 MV photon energy was used for 3D-CRT, IMRT and VMAT planning.Results: The rectum, bladder, right and left femur, body IDs, the homogeneity index (HI), and conformity index (CI) values were found to be higher in 3D-CRT planning compared to IMRT and VMAT planning (p < 0.001). The body mean, and ID were lower in VMAT planning compared to IMRT and 3D-CRT plans (p < 0.001). The monitor unit (MU) value was significantly higher in the IMRT planning compared to VMAT and 3D-CRT plans, and higher in the VMAT plan compared to 3D-CRT plans (p < 0.001).Conclusion: According to our study, for organ protection, body ID doses and HI, as well as CI, the VMAT planning technique is mostly superior to IMRT and 3D-CRT. In terms of MU, the 3D-CRT planning technique is better than the others. Our findings indicate that VMAT could generate plans that deliver lower IDs to healthy tissues while providing relatively uniform doses to the target area; and lower MUs.