Production and quality control of 82mRb and primary PET scans using its radiopharmaceutical for heart examinations [Persian]
نویسندگان
1 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
2 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
3 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
4 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
5 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
6 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
7 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
8 Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
doi
چکیده
According to the importance of positron emitters in nuclear medicine, 82mRb was produced as a member of this group of radiopharmaceuticals. After being converted into an injectable form, enough information was provided for imaging with this radiopharmaceutical. 82mRb with high radioisotopic purity and half-life of 6.5 hours, in chloride form, can be considered as a suitable positron emitter for the assessment of myocardial function. As a result of the bombardment of 82Kr with 15.4 MeV protons, the activity of 35.04 mCi was finally achieved. The nuclear reaction efficiency was 6.37 mCi/μAh. The product had a high radiopharmaceutical purity, according to international standards.
