The Effect of Aquous Extract of Cariandrum Sativum on Fetal Weight and Height in Pregnant Mice
نویسندگان
1 Stem Cell Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2 Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3 Science and Research Branch, Islamic Azad University, Fars, Iran
4 Traditional Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
5 Comparative and Experimental Medicine Center, Shiraz University of Medical Sciences, Shiraz, Iran
6 Science and Research Branch, Islamic Azad University, Fars, Iran
doi
10.30476/ijns.2019.82958.1028چکیده
Background: Herbal medicine may have irreparable effects on fetal development. This study investigated the effect of Cariandrumsativum (coriander) aquous extract on mice fetal height and weight. Methods:In an experimental study, 120 pregnant mice were divided into four equal groups. The control group was without any intervention. The experimental group received 3500, 5000 and 6500 mg/kg of aquous extract of coriander. The height and weight of the embryos were recorded in first, second and third week of pregnancy. Results: The height and weight of embryos in experimental groups in first, second and third week was significantly lower than the control group. Conclusion: Coriander (C. Sativum) aquous extract was shown to reduce the fetal height and weight in a dose-dependent manner. These findings can be added to the literature when coriander is going to be used during pregnancy.
