Investigating the Clinical Course of COVID-19 Patients and its Relationship with Vaccine Administration
نویسندگان
1 Iranian Research Center on Healthy Aging, Prehospital medical emergencies Department, Faculty of Paramedics, Sabzevar University of Medical Sciences, Sabzevar, Iran
2 Non-Communicable Disease Research Center, Departman of Anesthesia, Faculty of Paramedices, Sabzevar University of Medical Sceinces, Sabzevar, Iran
3 Social Medicine Department, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
4 Non-communicable Diseases Research Center, Departman of Anesthesia, Faculty of Paramedices, Sabzevar University of Medical Sciences, Sabzevar, Iran
5 Non-communicable Diseases Research Center, Department of Operating Room, Faculty of Paramedices, Sabzevar University of Medical Sciences, Sabzevar, Iran
6 Iranian Research Center on Healthy Aging, Department of Operating Room, Faculty of Paramedices, Sabzevar University of Medical Sciences, Sabzevar, Iran
7 PhD Candidate in medical education, Department of Medical Education, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
8 Department of Biochemistry and Nutrition, Sabzevar University of Medical Sciences, Sabzevar, Iran
doi
10.30483/rjm.2025.254636.1413چکیده
Background: Assessing and monitoring the clinical progression of COVID-19 can provide valuable insights for developing effective treatment protocols and improving patient stability after discharge. This study aims to assess the clinical course of COVID-19 patients and their association with the administration of recommended vaccines. Objectives: Investigating the clinical course of COVID-19 and its relationship with vaccine administration. Methods: A cross-sectional study was conducted on 140 patients with COVID-19 who were discharged from Vasei Hospital, Sabzevar, Iran, between February and July 2022. Participants were selected via convenience sampling. A researcher-developed questionnaire was used to evaluate recovery progress at 4 and 12 weeks' post-discharge. Data were analyzed using SPSS v.24 with a significance level of 0.05. Results: The administration of recommended vaccine doses showed a significant relationship with the recovery rate at the second follow-up (12 weeks, P = 0.026), but not at the first follow-up (4 weeks). A significant relationship was found between the PCR test result at the second period and the recovery rate at the first follow-up (P = 0.002), but not at the second follow-up (P = 0.51). Conclusion: The study findings indicate that vaccination impacts both immunity levels and the long-term recovery of patients with COVID-19.
