SYNTHESES AND ANTIFUNGAL ACTIVITY OF 3-ARYLMETHYL-5-ARYLOXY METHYL-2- METHY LISOXAZOLIDINES

نویسندگان
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چکیده

Reaction of sodium salt of allyl alcohol with 2-chloro-5-phenyl- l,3,4-thiadiazole gave 2-allyloxy-5-phenyl-1,3,4-thiadiazole 2. Compounds 4a and 4b could be obtained through the reaction of nitrone 3 with 2. Reaction of compound 2 with nitrone 5 afforded the final compound 6. Antifungal activity of all compounds was less than ketoconazole

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