فهرست نشریات علمی دسترسی آزاد ایران

The relationship between aluminium toxicity and iron metabolism was studied. Male rats were exposed to aluminium by daily intraperitoneal injection of 40pmolelkg body weight. After 45 days, aluminium intoxified rats had a significant loweredserum ferritin (55%), iron (42%), TIBC (25%) and hemoglobin(31%). At thesame time the serum ceruloplasmin level was elevated by 60%. This result shows that aluminium interferes with the iron metabolism in rats and might be considered as a possiblecause of hypochromic microcytic anemia which is found following regular hemodialysis in chronic renal failure patients