A Fast and Efficient Method for the Synthesis of 1,5-Benzodiazepine Derivatives Under Solvent-Free Conditions

نویسندگان
Maleki, Ali ID 1
Shaabani, Ahmad ID 2

1 Department of Chemistry, Shahid Beheshti University, P.O. Box 19396-4717 Tehran, I.R. IRAN

2 Department of Chemistry, Shahid Beheshti University, P.O. Box 19396-4717 Tehran, I.R. IRAN

doi
10.30492/ijcce.2007.7608
چکیده

Silica sulfuric acid is found to catalyze efficiently the condensation of o-phenylenediamines with various linear and cyclic ketones to afford the corresponding 1,5-benzodiazepines in quantitative yields under solvent-free conditions at room temperature

کلیدواژه‌ها
1, 5-Benzodiazepine, Ortho-phenylenediamine, Solid acid catalyst, Silica sulfuric acid, Synthesis