فهرست نشریات علمی دسترسی آزاد ایران

Silica boron sulfonic acid [SiO 2 –B(OSO 3 H) 3 ] as an inexpensive, reusable, and Lewis and Brønsted acid catalyst was successfully synthesized, and used for the one-pot three-components synthesis of biologically active substituted Hantzsch 1,4-dihydropyridine derivatives  in the absence of solvent at 90ºC. Silica boron sulfonic acid is attractive and efficient, because it plays in two role as a Lewis acid (by boron atom) and also as a Brønsted acid (by OSO 3 H group), which can have a  better effect in reaction. The reaction was carried out under solvent-free and mild conditions. Silica boron sulfonic acid can be recovered and reused for at least five consecutive runs.