Novel Three-Step Synthesis of Imidazo[1,2-c]quinazoline-5(6H)-thione Derivatives

نویسندگان

1 دانشگاه آزاد اسلامی

2

doi
10.22059/jsciences.2018.64790
چکیده

A novel synthesis of Iimidazo[1,2-c]quinazoline-5(6 H )-thione framework was developed through a three-step reaction starting from benzil. The resulting (2-nitrophenyl)-4,5-diphenyl-1 H -imidazole  from the reaction of benzil and different 2-nitrobenzaldehyde, reduction of nitro group and then cyclization reaction with carbon disulfide (CS 2 ). All steps were carried out under easy and user-friendly conditions in short time without using expensive catalysts or reagents.