Fe(HSO4)3-Catalyzed Direct Conversion of Aldehydes into Nitriles Using Hydroxylamine Hydrochloride

نویسندگان
جعفری جواد ID 1
شرافتی شاهین ID 2
متین روشنی ID 3
پناهی مهدی ID 4

1 دانشگاه علامه طباطبایی

2 دانشگاه آزاد اسلامی

3 دانشگاه آزاد اسلامی

4 دانشگاه علوم بهزیستی و توانبخشی

doi
10.22036/org.chem.2017.75197.1084
چکیده

Due to the importance and various applications of nitriles especially in medicinal productions, a new method for conversion of aldehydes to nitriles has been presented. Several nitrile-containing aromatic compounds were synthesized through the treatment of various aldehydes and hydroxylamine hydrochloride as nucleophile in the presence of ferric hydrogen sulfate as a heterogeneous, efficient, and recyclable catalyst in DMF in good to excellent yields.

کلیدواژه‌ها
hydroxylamine hydrochloride, Ferric hydrogen sulfate, Nitriles, Aldehydes