فهرست نشریات علمی دسترسی آزاد ایران

Background and Objective: High-altitude environments pose challenges for broiler chickens, causing hypoxia, reduced growth rates, and increased disease susceptibility. This stress affects their cardiovascular and respiratory systems. This study explores the impact of L-carnitine and emulsifiers on lipid peroxidation, nitrite production (as an indicator of nitric oxide), and the heterophil/lymphocyte ratio in chickens experiencing high-altitude stress.Materials and Methods: Broiler chicks were raised at high altitudes (2100 m) for 42 days, divided into a control and three treatment groups receiving L-carnitine, emulsifier, or both. Blood samples were collected to analyze nitrite and malondialdehyde (MDA) levels. The heterophil/lymphocyte (H/L) ratio was determined from blood smearsResults: Nitrite levels were increased in the L-carnitine and L-carnitine + emulsifier groups compared to controls, while MDA levels decreased in both treatment groups compared to controls (P<0.05). Additionally, the H/L ratio was significantly reduced in all treatment groups compared to the control group (P<0.05).Conclusion: This study determined the significant benefits of L-carnitine and emulsifiers in improving the adverse effects of high-altitude conditions such as oxidative stress, vasoconstriction, and hypertension in broiler chickens.