فهرست نشریات علمی دسترسی آزاد ایران

Inflammatory bowel disease (IBD) is a chronic, idiopathic, and irreversible disorder affecting the intestines,commonly presenting as Crohn’s disease (CD) and ulcerative colitis (UC). Although the precise cause remainsunknown, substantial evidence points to genetic predisposition, environmental factors, nutritional influences, andimmune system dysfunction as significant contributors to disease development and progression. Furthermore,research highlights the impact of oxidative stress, along with viral, microbial, and parasitic infections, inaggravating IBD symptoms. While no definitive cure exists, various therapeutic approaches ranging fromtraditional medications to innovative biologic treatments are employed to manage and reduce symptoms. Overrecent decades, standard options such as aminosalicylates, corticosteroids, and immunomodulators have beenwidely used, with biologic agents like infliximab offering additional benefits for some patients. Nonetheless, thelimitations of these therapies emphasize the pressing need for more effective and alternative strategies. In thisregard, ethnomedicinal studies have increasingly investigated plant-based remedies for inflammatory conditions,with notable attention given to the Lamiaceae family due to its strong anti-inflammatory properties. This reviewexplores the therapeutic potential of approximately 37 Lamiaceae species, assessing their role in IBD managementand their viability as complementary or alternative options to existing treatments.