فهرست نشریات علمی دسترسی آزاد ایران

This research aimed to evaluate the antimicrobial, antioxidant, and lipase inhibitory properties of leaf extracts fromMoringa peregrina (M. peregrina) and Murraya koenigii (M. koenigii). Antioxidant capacity was assessed using theABTS method, while total phenol content was measured via the Folin-Ciocalteu method. The antifungal activityagainst Candida albicans was determined through zone inhibition assays, and the ability to inhibit Helicobacterpylori was evaluated by measuring urease enzyme activity. Lipase activity inhibition was assessed using ELISA at405 nm. Analysis of variance revealed that increasing concentrations of both extracts significantly enhancedantioxidant activity and total phenol content (p<0.05). M. peregrina and M. koenigii exhibited the highestantioxidant activity at 4000 mg/L, while M. koenigii showed the lowest activity at 31.25 mg/L. The highest totalphenol content occurred at 4000 mg/L for M. koenigii. Synergistic effects of both extracts were noted at 1000 mg/L.At 1500 mg/L, M. peregrina displayed the largest inhibition zone against Candida albicans; conversely, M. koenigiishowed the strongest inhibition of Helicobacter pylori at 2000 mg/L. The greatest lipase inhibitory activity wasfound at 4000 mg/L for M. peregrina, while M. koenigii had the least at 2000 mg/L, and there were no synergisticeffects. These findings suggest that M. peregrina and M. koenigii leaf extracts have potential applications indeveloping anti-diabetic food products.