فهرست نشریات علمی دسترسی آزاد ایران

Berry fruits are of great nutritional and medicinal importance due to their polyphenolic compounds. The current research provided a comparative study of the polyphenolic compounds and bioactive activities of three fruits, currants (grapes), raspberries and strawberries, cultivated in the Almaty region of Kazakhstan. Polyphenolic compounds were determined using high-performance liquid chromatography and antioxidant activity was determined using two assays, DPPH and FRAP, and also for the alpha-glucosidase and acetylcholinesterase enzyme inhibitory activities. Quantitative analysis indicated that there were significant differences in the polyphenolic profile of these fruits. Total polyphenol content in strawberry (520.6 mg g-1 dry weight) was significantly higher than raspberry (452.8) and currant (385.5). Strawberries had a very high content of this compound, i.e., 223 mg/100 g dry weight of anthocyanins. Raspberries, however, had the highest content of ellagitannins (158.4 mg/100 g dry weight) and had the highest DPPH free radical inhibitory activity (IC₅₀ value of 38.5 μg mL-1). Currants were also the richest in these compounds and had 1.151 mg/100 g dry weight of flavonols. In the enzyme inhibition test, raspberries were the most potent inhibitors of the enzymes alpha-glucosidase (IC₅₀ = 0.65 mg mL-1) and acetylcholinesterase (IC₅₀ = 1.15 mg mL-1). The results of this research clearly show that all these fruits possess a unique chemical fingerprint and hence have varying health-promoting potential, which can be utilized as a scientific basis for the development of targeted nutraceutical products.