Uranium associations with kidney disease of South Kazakhstan uranium region population
نویسندگان
1 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
2 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
3 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
4 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
5 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
6 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
7 Department of Internal Medicine with a Course of Nephrology, Haematology, Allergology and Immunology of the nJSC, Astana Medical University, Astana, Kazakhstan
8 Scientific Research Institute of Radiobiology and Radiation Protection of the nJSC, Astana Medical University, Astana, Kazakhstan
9 Department of Eye Diseases of the nJSC, Astana Medical University, Astana, Kazakhstan
doi
10.22124/cjes.2024.7600چکیده
Uranium mining activities in South Kazakhstan may result in environmental pollution that may affect the health of people living in the uranium industry operating area due to the dangerous toxic and radioactive properties of uranium. In preliminary studies it was shown that the inhabitants of the uranium ore province of Syrdarya are dominated by the pathology of the urinary system. We conducted a retrospective cohort study to assess the prevalence of kidney disease and urinary uranium concentrations in adults living in close proximity to a uranium mine. The study included the entire population, men and women over the age of 18 diagnosed with kidney disease. The uranium concentration in daily urine samples was determined on a mass spectrometer with inductively coupled plasma. The prevalence of kidney pathology in the population of the main group was 239.5 per 1000 people, statistically significantly exceeding this indicator in the control groups by 1.3-1.5 times. At the same time, we determined the relationship between kidney diseases and gender, employment status and length of stay in the Uranium Ore Province territory. The uranium content in the urine of the residents of the village of Bidaykol was higher than in the control groups. This study provides fundamental and useful information to address public health and environmental concerns in the uranium mining areas of Kazakhstan.
