Direct azido-halogenation of olefins: A comprehensive review
نویسندگان
1 Tashkent State Pedagogical University, Tashkent, Uzbekistan.
2 Faculty of Chemistry, National University of Uzbekistan named after Mirzo Ulugbek, Tashkent, Uzbekistan.
3 Urgench State Pedagogical Institute, Urgench, Uzbekistan.
4 Department of Transport Systems, Urgench State University named after Abu Raykhan Beruni, Urgench, Uzbekistan.
5 Department of Biology, Bukhara State University, Bukhara, Uzbekistan.
6 Department of Hygiene №2, Bukhara State Medical Institute named after Abu Ali ibn Sino, Bukhara, Uzbekistan.
7 Department of Irrigation and Reclamation, Tashkent Institute of Irrigation and Agricultural Mechanization Engineers, National Research University, Tashkent, Uzbekistan.
8 Azerbaijan State Oil and Industry University, Baku, Azerbaijan.
9 Department of Informatics and Information Technologies, Chirchik State Pedagogical University, Chirchik, Uzbekistan.
10 Bukhara State Pedagogical Institute, Bukhara, Uzbekistan.
doi
10.22034/crl.2025.552717.1707چکیده
This review comprehensively covers both recent and foundational studies on the direct vicinal azido-halogenation of alkenes to produce 1,2-haloazides. It is organized into four main sections based on the halogen involved: (i) azido-fluorination, (ii) azido-bromination, (iii) azido-chlorination, and (iv) azido-iodination. Within each section, the reactions are further classified by their regioselectivity, highlighting Markovnikov versus anti-Markovnikov outcomes to provide insight into their mechanistic pathways and selectivity patterns.
