A Review of Synthesis, Antioxidant and Antimicrobial Activities of New Thiazole Derivatives

نویسندگان

1 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region – F.R. Iraq

2 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region – F.R. Iraq

3 Centre for Research Impact & Outcome, Chitkara University Institute of Engineering and Technology, Chitkara University, Rajpura, 140401, Punjab, India

4 Department of Chemistry, Faculty of Science and Health, Koya University, Koya KOY45, Kurdistan Region - F.R. Iraq

5 Department of Medical Laboratory Science, College of Science, Knowledge University, Erbil, 44001, F.R. Iraq

doi
10.22034/crl.2025.504852.1537
چکیده

Thiazole derivatives, a type of heterocyclic compounds, have gained significant attention in the field of medicinal chemistry due to their diverse pharmacological activities. They play a crucial role in the pharmaceutical industry because of their unique properties. This review aims to thoroughly examine the existing literature on thiazole derivatives, specifically focusing on their antioxidant and antimicrobial activities. Recent research has mainly concentrated on investigating the antioxidant properties of these derivatives. The review systematically explores numerous studies that have looked into the radical-scavenging abilities and modulation of enzymatic antioxidant defenses exhibited by thiazole derivatives. Additionally, it conducts a comprehensive analysis of the impact of structural modifications on the effectiveness of antioxidants. In terms of antimicrobial activity, thiazole derivatives have shown significant efficacy against a wide range of microorganisms.