Halosulfenylation of indoles: A review
نویسندگان
1 College of Food Sciences, Al-Qasim Green University, Babylon, Iraq
2 Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq
3 College of MLT, Ahl Al Bayt University, Iraq
4 Collage of Pharmacy, National University of Science and Technology, Dhi Qar, 64001, Iraq
5 College of Pharmacy, Alnoor University, Mosul, Iraq
6 Gilgamesh Ahliya University, Baghdad, Iraq
7 Medical technical college, Al-Farahidi University, Iraq
doi
10.22034/crl.2024.480280.1429چکیده
The direct vicinal difunctionalization of heteroarenes has emerged as a powerful approach for rapid increase of molecular complexity in one synthetic step. In this context, halosulfenylation of indoles have recently observed considerable attention not only because of diverse biological activities of thioindoles, but also because of usefulness of carbon-halogen bonds for further synthetic transformations using different convenient reactions. In this Focus-Review, we summarize the available literature on this novel and rapidly growing research topic by hoping that it will serve to stimulate further research and thinking in this area.