A Review: New Synthesis of Chalcone Derivatives and Their Applications
نویسندگان
1 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region - F.R. Iraq.
2 Department of Nursing, Raparin Technical and Vocational Institute, Rania, Sulaymaniyah, Kurdistan Region, 46012, Iraq
3 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region - F.R. Iraq.
4 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region - F.R. Iraq.
5 Department of Chemistry, Faculty of Science and Health, Koya University, Danielle Mitterrand Boulevard, Koya KOY45, Kurdistan Region - F.R. Iraq.
6 Department of Chemistry, College of Education, University of Garmian, 46021 Kalar, Kurdistan Region – F.R., Iraq
7 Department of Medical Laboratory Science, College of Science, Knowledge University, Erbil, 44001, Iraq
doi
10.22034/crl.2025.480229.1427چکیده
Chalcones, also known as 1,3-diphenyl-2-propene-1-one, are organic substances composed of two aromatic rings connected by an unsaturated carbonyl group. These compounds belong to the flavonoid family and serve as precursors to other flavonoids found in a variety of plants. Naturally occurring in tea, fruits, vegetables, and spices, chalcones can be chemically synthesized through the Claisen-Schmidt condensation reaction, along with other methods like microwave irradiation and the Suzuki reaction. Chalcones and their derivatives exhibit a wide range of biological effects, including antibacterial, anticancer, and anti-inflammatory properties.
