Magnetic Resonance Imaging Features of Olfactory Neuroendocrine Carcinoma in a Dog
نویسندگان
1 Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
2 Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
3 Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
4 Cancer Biology Research Center, Cancer Institute of Iran, Tehran University of Medical Science, Tehran, Iran.
5 Division of Epidemiology & Zoonoses, Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
doi
10.32598/ijvm.18.3.1005276چکیده
Olfactory neuroendocrine carcinoma is rare in small animals. A 4-year-old female mix-breed dog in a stupor state was presented with a history of weight loss, cachexia, paroxysm, ptyalism, absence of the light reflex in the left eye, and grade 4 lameness in the left forelimb. In the magnetic resonance imaging (MRI) images, an extra-axial space occupying a mass lesion was detected extending directly from the nasal fossa to the bulbous olfactorius of the frontal cerebral lobe through the destructed cribriform plate, consistent with high-grade nasocranial neoplasia. Histopathological findings confirmed high-grade olfactory neuroendocrine carcinoma.