Strategies for the lactamization/lactonization of 2-arylanilines/2-arylphenols using CO2 as C1 source
نویسندگان
1 College of Pharmacy,Alnoor University,Mosul,Iraq
2 College of MLT, Ahl Al Bayt University, Iraq
3 Al-Zahrawi University College, Karbala, Iraq
4 Gilgamesh Ahliya University, Baghdad, Iraq
5 Collage of Pharmacy, National University of Science and Technology, Dhi Qar, 64001, Iraq
6 Medical technical college, Al-Farahidi University, Iraq
7 University of Tehran, Tehran, Iran
doi
10.22034/crl.2024.464140.1361چکیده
Phenanthridin-6(5H)-ones and 6H-benzo[c]chromen-6-ones are important tricyclic heterocycles found in several natural products and biologically active compounds. Besides classical synthetic methods, recently, many exciting advances in the synthesis of these classes of compounds have been reported. One of the most appealing strategies to obtain these heterocyclic motifs consists the direct lactamization/lactonization of 2-arylanilines/2-arylphenols using CO2 as C1 source. In this review, recent advances involving the synthesis of phenanthridin-6(5H)-one and 6H-benzo[c]chromen-6-one derivatives through the lactamization and lactonization of 2-arylanilines and 2-arylphenols, respectively, with CO2 are summarized. The review covers the period from April 2016 to June 2024.
