Synthesis of azo compounds containing salicylic acid and its derivatives: A review
نویسندگان
1 Department of Chemistry, Faculty of Science and Health, Koya University
2 Department of Physics, College of Science, University of Raparin
3 Department of Chemistry, Faculty of Science and Health, Koya University
4 Department of Chemistry, College of Education, University of Garmian
doi
10.22034/crl.2024.467469.1376چکیده
Azo compound derivatives, which are organic molecules with a double bond between two nitrogen atoms, have been extensively studied in scientific research. The predominant technique for producing these compounds entails the reaction between an aromatic amine and a diazonium salt. The synthesis usually employs starting materials such as salicylic acid, 3-ASA, 4-ASA, 5-ASA, and its derivatives. The synthesis process initiates by transforming the amine group of the initial substance into a diazonium salt utilizing of sodium nitrite and hydrochloric acid. The subsequent stage involves a coupling process between the diazonium salt and salicylic acid or its derivatives. This paper specifically examines creating a diverse array of azo compounds, emphasizing their multiple uses as synthetic materials, artificial acceptors, molecular ligands, and agrochemicals. These chemicals demonstrate substantial biological action, namely in terms of their anti-inflammatory, antibacterial, antifungal, antiviral, and antidiabetic activities.
