One-pot multicomponent reactions of isatins: Green synthesis of cyclopentatriazine derivatives by employing Ag/Fe3O4/SiO2@MWCNTs MNCs as an efficient catalyst
نویسندگان
1 College of MLT, Ahl Al Bayt University, Iraq
2 Gilgamesh Ahliya University, Baghdad, Iraq
3 Collage of Pharmacy, National University of Science and Technology, Dhi Qar, 64001, Iraq
4 Department of Pharmacy, Al-Zahrawi University College, Karbala, Iraq
5 College of Pharmacy, Alnoor University, Mosul, Iraq
6 Medical Laboratory Science Department, College of Health Science, University of Human Development, Sulaimanyiah, Kurdistan region of Iraq
7 Medical technical college, Al-Farahidi University, Iraq
doi
10.22034/crl.2024.460102.1343چکیده
Using a multicomponent reaction of isatin or benzaldehydes, malononitrile, ethyl 2,4-dioxo-4-arylbutanoate, ammonium acetate, and hydrazonoyl chlorides in aqueous media at room temperature in the presence of Ag/Fe3O4/SiO2@MWCNTs MNCs, this research produced cyclopentatriazines as new derivatives with a high yield. Another investigation in this work examines the antioxidant properties of the produced cyclopentatriazine. The applied method for producing cyclopentatriazine demonstrated a number of desirable traits, including quick reactions, high yields of the final product, and straightforward separation of the product and catalyst from the reaction mixture.
