Synthesis of 2, 4 disubstituted 1, 5 benzodiazepines promoted by efficient Silica-Alumina Catalyst
نویسندگان
1 Mahant Jamnadas Maharaj Arts, Commerce and Science college, Karanjali, Nashik, India
2 Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad-431004, India
doi
10.22034/crl.2020.255303.1089چکیده
An efficient and environment friendly valuable synthon of 1, 5 benzodiazepine derivatives were synthesized having unique physical and medicinal properties. This reaction is performed by mesoporous binary mixed metal oxide SiO2-Al2O3 which is synthesized by hydrothermal method at high temperature. This mesoporous material is investigated by XRD, SEM, EDS, TEM, TPD and BET surface area. Present method offers several remarkable advantages such as non-toxic, noncorrosive and easy work-up procedure for the purification of product with non-chromatographic method, ecofriendly reaction condition.
