Cytotoxic study of green synthesized pure and Ag-doped α-Fe2O3 nanoparticles on breast cancer (MCF-7) cell line
نویسندگان
1 Salamat yar behesht dayan ,Dayan biotech company , Tehran, Iran
2 Centre for processing and charactrization of nanostructred materials, School of mechanical engineering, University of Tehran, Tehran Iran
3 Clinical Research Development Unit, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, Iran
4 Department of Oral and Maxillofacial surgery, School of Dentistry, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
5 Department of Neurology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Internal of Medicine, Faculty Member, Department of Medicine, Zabol University of Medical Sciences, Zabol, Iran
7 Department of Computer Science, Al-Turath University College, Al-Mansour, Baghdad, Iraq
doi
10.22034/nmrj.2022.04.007چکیده
In this research attempted to prepare hematite (α-Fe2O3) and silver doped hematite nanoparticles (Ag-doped α-Fe2O3 NPs) by using the aqueous extract of Prosopis farcta fruit. The synthesized NPs were identified through the results of X-ray Diffraction (XRD), Field Energy Scanning Electron Microscopy (FESEM), Raman, Energy Dispersive X-ray (EDX), and Vibrating Sample Magnetometer (VSM) technics. Accordingly, the NPs contained a spherical shape with a size range of 40-50 nm. Also, we surveyed their cytotoxic against human breast cancer (MCF-7) cell line, which showed a potential functionality at the concentration of 80 μg/mL. Therefore, the synthesized NPs can be proposed as an applicable candidate for medical applications.
