Evaluation of Toxicity of Engine oil Enriched with Copper Nanoparticles and its Impact on Pathology of Intestinal, Liver, Lung and Kidney Tissues
نویسندگان
1 Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
2 Department of Biology, Faculty of Basic Sciences, Behbahan Khatam Alanbia University of Technology, Behbahan, Iran.
3 Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
4 Department of Comparative Biosciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
doi
10.22034/nmrj.2020.01.002چکیده
Objective(s): Iranian researchers have enriched conventional engine oil with nanoparticles at the Institute of Petroleum Research and hope that this product can replace conventional engine oil due to the improved effects of copper nanoparticles on oils. the purpose of this study was to investigate the pathological effect of engine oil enriched with copper nanoparticles on the rat.Methods: In this study, 72 female rat were randomly divided into 8 experimental groups, and three treatment groups (repeated) oral doses of 2000 mg /kg and 5000 mg /kg engine oil containing and without copper nanoparticles in three treatment groups at 30 minutes, 4 hours and 24 hours.Results: In treatment group A and B, oral dose of 5000 mg/kg engine oil containing and without copper nanoparticles showed a significant positive correlation with lethality at 30 minutes, 4 hours and 24 hours. p
