Pluronic based nano-delivery systems; Prospective warrior in war against cancer
نویسندگان
1 Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2 Medical Biomaterials Research Center, Tehran University of Medical Sciences, Tehran, Iran
doi
10.7508/nmrj.2016.01.001چکیده
Pluronic based nano-particulate systems are innovative platforms for delivery of anti-cancer agents. These systems due to their pharmacological properties and suitable physicochemical characteristics are great opportunity for development cancer therapeutics. This mini-review tries to provide a more detailed overview on the currently available pluronic based drug delivery systems. In the section 2, pharmacological characteristics of pluronic as a therapeutic polymer are assessed. In section 3, pluronic based formulations for undruggable payloads and surfaced modified targeted delivery systems are analyzed. The combinatorial pluronic based systems are summarized in section 4 and at last but not least the challenges and future prospective are discussed within section 5.
