Effect of Antibiotic Prophylaxis in Preventing Wound Infection in Elective Clean Surgical Procedures
نویسندگان
1 Associate Professor of General Surgery, Iran University of Medical Sciences and Health Services, Hazrat Rasool Hospital, Tehran, Iran
2 Resident of General Surgery, Iran University of Medical Sciences and Health Services, Tehran, Iran
3 General Surgeon, Iran University of Medical Sciences and Health Services, Hazrat Rasool Hospital, Tehran, Iran
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چکیده
Introduction & Objective: Post operative wound infection is the most common form of infection insurgical patients, containing about 38% of all surgical infections. In the text books surgical wounds aredivided into 4 groups: clean, clean- contaminated, contaminated and dirty.Prophylactic antibiotic therapy is recommended only in clean -contaminated operations and is not routinein clean operations except for some special situations.However, prophylactic antibiotic therapy is used for all clean elective operations in Firoozgar hospital thathas some disadvantages, including resistant strains of bacteria, and financial problems (extra cost) for patients.This study was done to determine whether antibiotic prophylaxis is an effective method in preventing woundinfection in these operations or not.Materials & Methods: This interventional study (clinical trial) was done from June 2002 to May 2003on 121 patients in Firoozager hospital. Patients who were candidate for elective clean surgical proceduresdivided into two groups, according to randomized numbers.Results: 62 patients (51.2%) received prophylactic antibiotic and 89 patients (48.8%) received noprophylaxis. Wound infection occurred in 13 patients (10.7%), 7 patients (5.78%) in Control group and 6patients (4.95%) in antibiotic treatment group. There was no statistically significant difference between twogroups. (P=0.1).Conclusions: According to results of this study, routine use of antibiotic prophylaxis is notrecommended in clean elective operations.
