Role of Micro/Nano porous Activated Carbon Prepared from Black Olive Pits Against Oleandrin-Induced Toxicity in Vital Organs of Albino Rats
نویسندگان
1 Department of Pharmaceutics and Pharmaceutical Industry, Faculty of Pharmacy, Kufa University, Iraq
doi
10.22052/JNS.2026.02.025چکیده
In order to determine the impact of the oleandrin compound on specific essential organs( lung,stomach and intestines) of white rats both before and after the adsorption process, adsorption was carried out using activated carbon made from black olive pits gathered in Iraq. The findings showed that the oleandrin clearly had a detrimental effect on the organs under investigation before therapy. Nevertheless, a noticeable improvement was seen following adsorption onto the activated carbon, indicating that the adsorption method was successful in lowering the toxicity of the chemical and enhancing its biological response. Furthermore, a thorough analysis of the adsorption process was carried out, encompassing a number of influencing factors like temperature, pH, equilibrium time, and the ideal dosage of adsorbent. In order to ascertain the adsorption mechanism and gain a better understanding of the interaction between the oleandrin being studied and the adsorbent surface, kinetic experiments were also conducted, and the adsorption was of the pseudo-second-order type and coincided with the Freundlich isotherm.