فهرست نشریات علمی دسترسی آزاد ایران

Silver nanoparticles are widely applied in industrial and biomedical fields. Also, the silver nanoparticles show a capability against bacterial drug resistance bacteria. The unique final properties of the nanoparticle depend on the type, size, and shape of nanoparticles. We used leaves extract Arum elongatum in the present study to synthesize silver nanoparticles. The synthesized AgNPs were identified using UV-Vis, SEM, XRD, and FT-IR analysis. The UV-Vis analysis of AgNPs has exhibited an absorbance peak at 430 nm. The crystalline structure of the silver nanoparticles was determined by XRD analyses. The SEM analysis results indicated spherical shape aggregates with an average particle size between 9-11nm. Afterward, the antibacterial properties of the nanoparticles were studied by broth microdilution methods. The nanoparticles showed the antibacterial effect on all the pathogenic strains with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) in the range of 0.0312±0.00 to 0.5±0.00 and 0.125±0.00 to 2>±0.00mg/ml, respectively. The evaluation of antibiofilm activities of AgNPs against uropathogenic bacteria showed a potent biofilm inhibitory. Further, the cytotoxicity of AgNPs was determined using a brine shrimp lethality assay, and the LC50 value was 200 mg/ml.