Phytogenic Copper Oxide Nanoparticles Synthesized from Carica papaya Leaves: Characterization and Antibacterial–Antifungal Activity
نویسندگان
1 Department of Chemistry, College of Science, University of Diyala, Iraq
2 Department of Chemistry, College of Science, University of Diyala, Iraq
3 Department of Chemistry, College of Science, University of Diyala, Iraq
4 Department of Chemistry, College of Science, University of Diyala, Iraq
5 Department of Horticulture and landscape, Faculty of Agriculture, University of Diyala, Iraq
6 Department of Chemistry, College of Science, University of Diyala, Iraq
doi
10.22052/JNS.2026.02.042چکیده
This work presents an eco-friendly method for synthesizing copper oxide nanoparticles (CuO NPs) using Carica papaya leaf extract as a natural reducing and stabilizing agent. The preparing NPs were characterized by Fourier Transform Infrared Spectroscopy (FTIR), Brunauer-Emmett-Teller (BET), Transmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM), and X-Ray Diffraction Spectroscopy (XRD), confirming a cubical shape with average size of 40 to 60 nm. Antibacterial activity was investigated using the ager well diffusion method against both gram negative (and P. aeruginosa K. pneumonia) and gram positive (S. epidermidis and S. aureus), as well as, the fungus Candida albicans. The CuO NPs appeared considerably antibacterial activity, with inhibition zone of up to 19 mm for C. albicans and 15 mm for S. aureus with concentration of 30 mg/ml. These results suggest that CuO NPs prepared by green method offer promising potential for antimicrobial application.
